Thyroid Cancer

The thyroid gland, located in the lower front part of your neck just above the windpipe, is a small but vital organ. It consists of two lobes connected by a thin tissue bridge called the isthmus. A healthy thyroid gland is usually invisible and not easily felt by hand. Despite its small size, it plays a crucial role in regulating your body’s metabolism.

The thyroid gland secretes two main hormones: T3 (triiodothyronine) and T4 (thyroxine). These hormones control the body’s energy production and utilization, influencing heart rate, digestion, and even mood. The thyroid also produces a hormone called calcitonin via its parafollicular cells, which helps regulate calcium levels in bones, supporting bone health.

What Is Thyroid Cancer?

Thyroid cancer occurs when cells in the thyroid gland grow uncontrollably. Over time, these cells can form tumors and spread. Thyroid cancer is generally treatable when diagnosed early, but it can present in various forms, each requiring different approaches.

Thyroid cancer is often detected as a lump or swelling in the neck. In some cases, it is discovered incidentally during tests for other conditions.

Types of Thyroid Cancer

Thyroid cancer is categorized into four main types, each with distinct characteristics and treatment approaches:

1) Papillary Thyroid Cancer
The most common type, accounting for 80% of cases. It typically grows slowly and can spread to lymph nodes. It responds well to treatment, with high survival rates, and is more common in women aged 30-50.

2) Follicular Thyroid Cancer
Less common, representing about 4% of cases. It has a risk of spreading to bones and lungs and is generally more aggressive than papillary cancer. It is most frequently seen in middle-aged women.

3) Medullary Thyroid Cancer
A rare type originating from the thyroid’s calcitonin-producing cells. Approximately 25% of cases are linked to genetic mutations. Those with a family history of medullary thyroid cancer may consider genetic testing.

4) Anaplastic Thyroid Cancer
The rarest and most aggressive form. It typically occurs in older individuals and has a high tendency to spread rapidly, making it more challenging to treat.

Who Is at Risk?

The exact cause of thyroid cancer is not fully understood, but several factors increase the risk:

  • Gender: Thyroid cancer is three times more common in women than in men.
  • Age: Papillary and follicular cancers are often seen in individuals aged 30-50, while anaplastic cancer occurs later in life.
  • Family History: A family history of thyroid cancer increases risk, especially for medullary thyroid cancer with a genetic basis.
  • Radiation Exposure: Individuals who received radiation therapy to the neck in childhood are at higher risk.
  • Genetic Mutations: Specific genetic changes, such as mutations in the RET gene, can elevate risk.
  • Thyroid Conditions: Benign thyroid conditions, such as goiter, may slightly increase risk.

Symptoms of Thyroid Cancer

Thyroid cancer often does not cause symptoms in its early stages. However, as it progresses, the following symptoms may appear:

  • A noticeable lump or swelling in the neck
  • Hoarseness or changes in voice
  • Difficulty swallowing
  • Breathing difficulties
  • Neck or throat pain
  • Swollen lymph nodes

These symptoms can be caused by other conditions, but if you notice them, it is essential to consult a doctor.

How Is Thyroid Cancer Diagnosed?

If you have a neck swelling or any of the symptoms listed, your doctor may perform several tests:

1) Physical Examination: The doctor will examine your neck and ask about your medical history.

2) Ultrasound: Used to assess the thyroid and nearby lymph nodes.

3) Fine-Needle Aspiration Biopsy: A small tissue sample is taken from a suspicious lump and examined under a microscope. This is the most definitive test for confirming cancer.

4) Blood Tests: Check thyroid hormone levels and markers associated with certain cancer types.

5) CT and MRI Scans: Provide detailed images to determine whether the cancer has spread.

How Is Thyroid Cancer Treated?

Treatment depends on the type and stage of cancer. Common treatment methods include:

  • Surgery: The thyroid gland may be partially or entirely removed. Lymph nodes may also be removed.
  • Radioactive Iodine Therapy: Used after surgery to destroy any remaining cancer cells.
  • Hormone Therapy: If the thyroid gland is removed, hormone replacement therapy is administered to maintain normal body functions.

Can Thyroid Cancer Be Prevented?

While it cannot be entirely prevented, the following steps can reduce the risk:

  • Avoid unnecessary radiation exposure.
  • Undergo regular check-ups if you have a family history of thyroid cancer.
  • Adopt a healthy lifestyle with a balanced diet and avoid smoking.

Are Routine Screenings Necessary?

Routine screening for thyroid cancer is not recommended for the general population. However, high-risk individuals (e.g., those with a family history of medullary thyroid cancer) may benefit from regular blood tests and ultrasounds.

Summary

Thyroid cancer is highly treatable with early detection and appropriate treatment methods. If you notice any abnormalities in your neck or experience the symptoms mentioned above, consult a doctor without delay. Remember, your health is invaluable, and early detection can save lives!

Prof. Dr. Gediz Murat Serin

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    Prof. Dr. Gediz Murat Serin